The cosmetic form of botulinum toxin, sometimes referred to as "botox" by patients, is a popular injectable that temporarily reduces or eliminates wrinkles. The most commonly treated areas are frown lines, forehead creases, and crow's feet near the eyes. Several other areas have been treated such as thick bands in the neck, thick jaw muscles, lip lines and gummy smiles.
A forma cosmética da toxina botulínica, às vezes chamada de "botox" pelos pacientes, é um injetável popular que reduz ou elimina rugas temporariamente. As áreas mais comumente tratadas são rugas entre sobrancelhas, vincos na testa e pés de galinha. Várias outras áreas são tratadas, como bandas grossas no pescoço, músculos grossos da mandíbula, linhas dos lábios e sorrisos gengivais.
Botulinum toxin is a purified substance that's derived from bacteria. Injections of botulinum toxin block the nerve signals to the muscle in which it was injected. Without a signal, the muscle is not able to contract. The end result is diminished unwanted facial wrinkles and fine lines. Commonly known brands of botulinum toxin type A injections include Botox®, Dysport®, Xeomin® and Jeuveau®.
A toxina botulínica é uma substância purificada derivada de bactérias. As injeções de toxina botulínica bloqueiam os sinais nervosos para o músculo no qual foi injetado. Sem um sinal, o músculo não consegue se contrair. O resultado final é a diminuição de rugas e marcas de expressão. Marcas comumente conhecidas de injeções de toxina botulínica tipo A incluem Botox®, Dysport®, Xeomin® e Jeuveau®.
Botox® is very popular. However, its rise to fame began almost 150 years ago.
1895 - Professor Emile Emargem identified the bacteria Clostridum botulinum
1946 - Researchers purified the toxin produced by Clostridum botulinum into a crystalline form.
1953 - Physiologist Vernon Brooks discovers that the toxin causes temporary muscle relaxation
1960 - Ophthalmologist Allan Scott uses toxin as a treatment for strabismus (crossed eyes)
1988 - Allergan acquired the rights to distribute botulinum toxin and named it Botox (what a great investment!)
1989 - FDA approves Botox for strabismus and eyelid spasms
1990 - Ophthalmologist Jean Carruthers realized people using Botox had no wrinkles between eyebrows (talk about an ah-ha moment!)
2000 - FDA approves Botox for cervical dystonia
2002 - FDA approves Botox for frown lines between the eyebrows
2004 - FDA approves Botox for excessive sweating under arms
2010 - FDA approves Botox for chronic migraine
2019 - FDA approves Botox for spasticity on pediatric patients.